Huda Y. Zoghbi, M.D.

Jan and Dan Duncan
Neurological Research Institute

Where breakthroughs begin

The biggest surprise is to see how much has been accomplished in so many areas that benefit all populations with neurological disorders. Moving into therapy is not something we expected to happen in such a short period of time.
— Huda Y. Zoghbi, M.D., Director, Jan and Dan Neurological Research Institute

The Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital seeks to change lives by understanding the genetic causes of pediatric and adult neurological diseases. These devastating conditions impact 1 billion people – including 300 million children – worldwide.

By building an understanding of what causes conditions like autism and epilepsy, we can then move on to find treatments—and one day, maybe even cures.

Since opening its doors in 2010, we’ve made rapid progress in understanding and exploring new treatments for a host of neurological conditions including epilepsy, autism, Alzheimer’s, traumatic brain injury, Huntington’s, Batten disease, Parkinson’s, brain tumors and more.

These discoveries depend on a whole team of people working together on both basic and clinical research. Collaboration among many different types of experts in genetics, behavioral science, physiology, engineering and computational science makes us unique and highly successful at finding answers to these perplexing conditions.

This work also depends on donations to fund cutting-edge research.

The NRI began thanks to transformational gifts from philanthropists Cynthia and Anthony Petrello and Jan and Dan Duncan. Many more benefactors continue to fund this life-saving work with donations large and small. Your support is needed to help the NRI find answers and identify potential treatments for what used to be fatal conditions.