When Dr. Huda Zoghbi left war-torn Lebanon in the 1970s to attend medical school in the U.S., little did she know that her journey would bring her to Texas Children’s Hospital. Today, she is a world-renowned neurogeneticist and director of the Jan and Dan Duncan Neurological Research Institute (NRI), where she leads a team dedicated to finding more effective treatments for a host of devastating neurological disorders.

One of those disorders is caused by a unique genetic mutation—a mutation identified in Henry Engel, the three-and-a-half-year-old son of NBC Chief Foreign Correspondent Richard Engel and his wife, Mary Forrest.

Watch the NBC Today Show segment about Dr. Zoghbi and the work she and her team at the NRI are doing to help Henry and millions of children and adults with neurological disorders around the world.